Hyaluronic acid is a linear polysaccharide composed of repeating disaccharide units containing D-glucuronic acid and N-acetyl glucosamine. Hyaluronic acid is natural substance in human body where it occurs in form of sodium or other salts. It is one of the chief components of the extracellular matrix with its high concentrations found mainly in eyes, joints and skin.
As the human body grows older, its amount diminishes. That can lead to decrease in flexibility of cartilages, joints and tendons, reduction in skin elasticity and other with that related symptoms. For these reasons it´s recommended to supplement it to our bodies. That´s why hyaluronic acid is an active substance of various preparations used to enhance the wounds healing and recovery after eye surgeries and to fight many joint and skin diseases.
Use in cosmetics:
Hyaluronic acid acts as a natural hydrating agent because it can bind up to 4000 times more water than it actually weights. More than 50% of its content in human body is located in skin. For this reason it has a wide use in cosmetics.
Biological effects of hyaluronic acid vary depending on its molecular weight. Because of that we distinguish between the low molecular and high molecular hyaluronic acid.
Low molecular hyaluronic acid shows its biological activity in deeper skin layers where it stimulates skin cell, provides hydration and thus prevents formation of deep wrinkles.
On the other hand, high molecular hyaluronic acid acts as a humectant on the surface of the skin, regenerating it, protecting it from external influences and restoring its elasticity.
Hyaluronic acid has also a wide range of applications in healthcare, biotechnology and tissue engineering.
The team of Delga decided to rely on the unique properties of hyaluronic acid and formed a complex food supplement – oral drops (supplements the hyaluronic acid through internal administration) and topical preparation – gel (uses the effect of low and high molecular hyaluronic acid for perfect skincare).